I am so mad at the vet and think we should file suit against this company. Currently we are monitoring him closely-hes never been sick. My Irish setter is weak on her left side, left side of her face is drooping and she now carries her head with a tilt to the left. Head down, tail down, will stand in a corner and stare at the wall. Im still confused. Im so angry at these drug companies and vets for selling this crap. Wont use again. Two quick questionsDo the dogs eventually return to normal? Im not sure if the simperica is the cause. Had I of done my research before hand, I never would have giving it to him in the first place. Any advice on the diarrhea? Still waiting to find out of she has progressed. He looked like he was having a seizure. Nothing. My personal dog has had no issues at all, and she's been on it for nearly two years. Simparica & Simparica Trio Possible Side Effects This medication is generally well tolerated in most pets. The Simparica was recommended by the vet. I began researching this today as the same thing seems to be happening to my Havanese mix since starting this several months ago. Thank you for this. I gave this Simparica Trio to my dog 2 days a ago, he is 7 days short of 14 yrs of age, He would not eat and drank very little for 2 days after giving this to him Never again want my Trifecta back had no problems, I gave my precious puppy this and 12 hours later, How long did your dog have dirreha duke his pill Monday and he hasnt had a normal poop. I just hope and pray she gets better. Everything else in his environment, world has remained the same. I am extremely upset at myself for letting a similar but very serious threat get to my pup again. He walked outside peed then tried to come back in the house but his legs gave out . How did your baby do please? Simparica Trio is the first and only product that combines sarolaner, moxidectin and pyrantel in each treatment to help prevent heartworm disease, kill fleas before they can lay eggs, kill 5 types of ticks, treat and prevent flea infestations and treat and control roundworms and hookworms. I am so incredibly upset with myself for trusting my vet and giving my dog this product. I will use Sentinel and Pet Armor on her as this is what I have always gjven my dogs with no problems. This is taken from the article printed above all these comments "Simparica works by impacting the nervous system of invertebrates such as fleas and ticks. I am so sad to read what is happening to some pets. I hope these steps will prevent anyone else's pet having to endure this. He is otherwise normal and healthy. I feel like the simperica trio has somehow affected his Pituitary/Andrenal glands are maybe even acting as blockers to them. . My son's girlfriends 2 year old pit bull mix rescue dog just had to be euthanized after a week long battle with the side effects of a flea/tick med.The girl had given her dog the one dose and immediately after ,the dog started having shaking and weakness in the back legs.Took her to an emergency vet.Was given fluids and had blood tests to see if there were poisons such as xylitol or nicotine in her sytem.No problems.$900 later..jsu 2-3 hours on fluids she was released with no answers.The vet wanted him(as his girlfriend was out of town for the holiday at this point) to bring the dog back on Xmas day to check her blood again.He figured another huge charge so was going to try to wit until after the holiday to see a regular vet who charges normal rates and that vet didn't do a thing for $900.00.The dog got progressively worse.Couldn't walk ,couldn't eat ,couldn't bark.Eyes were darting from side to side.Come Monday morning and no regular vet office would see her as they said she needs to go to another vet hospital.They wanted 2,600.00 from my son right up front for an overnight stay.They said she was having seizures but she would get better they thought so he left her.The next morning they said she needed more days in the hospital.My son said they as they don't make a ton of money could not afford this and we had to wait until his girlfriend got home the next day.He wanted to take the dog home.They said they would keep the dog for free for 12 hours..Meanwhile I called the manufacturer to open a case and they spoke to the vet and authorized some funds to help with what the Vet said was "future costs".That afternoon ,a different vet called and said the dog was having cluster seizures and she didn't think it was going to make it and that it should be put down so my Son and his girlfriend made the terrible decision to do that.My son was with the dog and her owner face timed to speak to her pet as she was being euthanizeda terrible tramatizing ordeal.Next thing you know,my son gets the ivoice from the Vet and it is over 5,000.00. All they care about is the money and not the animal. Hi how is your pup now? Simparica Trio is not effective against adult heartworms. Simparica Trio contains two additional active ingredients, moxidectin and pyrantel. We are currently going through this with our nine year old dachshund. It's getting better and I decided to just wait and hope when this stuff clears out in 30 days he goes back to normal. PetArmor Plus Flea and Tick Prevention for Dogs, Dog Flea and Tick Treatment, Waterproof Topical, Fast Acting, Small Dogs (5-22 lbs), 6 Doses. Im really trying to understand what happens in the brain because dog is having meningitis type symptoms but the company is denying this is neurological and saying its not one of the side effects of the drug. Two weeks after I made the post above our girl started having seizures and we had to put her down. Hi, Im having similar issues. I cant believe how long this thread is. Its Sunday night and still vomiting. How long did it last with your dog? i know this med did this to her , she was on for a year and half , i should never ever have listened to the vet and went with my gut, but again they assured me since she was healthy be very rare she would have side effects smdh and plus been in contract with the makers of this horrible medication they all should be ashamed of themselves!!!!!!!!!!! The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. She is shaking and panting heavy. now seizures daily on all sorts of meds for it and the cost with medications to try and control seizures and vet visits and mainly seeing my once healthy playful full of life pups having seizures daily even in her sleep breaks my damn heart !!!!!!!!!!!!!! The Trio product by Simparica is a three-in-one medication to control and prevent flea, tick, and heartworm. We go for more bloodwork today and are praying for better news. He had no medical problems before this, and I took him to the vet every year he ended up dying two weeks later , I took him to the vet first they told me he wasnt gonna make it to leave him there and I told him no if he isnt gonna make it, hes going to pass away in my arms at home with me and his family why took him to a different vet not the same one I confronted the woman that gave me that medicine. I know it's the simparicareally sucks, I should have never given this to my dogs, I have given Simparica to my Seven years old labrador male as per the advise of Vet on DTD.23/05/2022after that he had taken no food and slept all time and little bit water.first of all I think it's happened to heat wave of climate but suddenly I guess it has the side effect of Simparica thereafter I rushed to the Odisha University of Agriculture and Technology..after blood testthe vet. No seizures yet thank goodness, but he is drinking a ton of water. We are experiencing the same thing. Hi, any chance you did a spinal tap? Omg this is horrible. 300+ Cute Cat Names for Every Kind of Kitty. 12/18/21.. he did experience some diarrhea. I gave my dog simparica at 10:15am. Been also very lethargic not wanting to get out of bed. Thanks! Compared to other products, the efficiency of this . Good luck. Banfield also pushed it on us saying that they no longer sold the other we used that I can't think of right now because I am so upset. Simparica Trio also prevents heartworms and keeps hookworms and roundworms from harming your pup. I called my vet but because of Covid they are so behind in appts and would not see him until a month from then. I feel like it was a massive overdose. One common alternative is to give Heartgard for heartworms and intestinal parasites along with Bravecto to prevent fleas and ticks, but there are other choices out there. I am trying to remain confident that my poor girl will recover. The following day he would not even drink water. This Tuesday the 17th I had given my dog simparica trio for 27lbs dose. Your vet should be able to answer any questions related to side effects, precautions, or special care for your dog. I was giving my 70 lb golden doodle Trifexus, for nearly 2 years until suddenly he refused to eat it. Doubtful our dog will be given Simparica again. The only thing the vet can say, was a sore neck. I tried everything but she just didnt have an appetite for anything. He is stumbling, not able to stand on tile or go in and out of house without tripping on steps. The main side effect of Simparica Trio is the risk of heartworm disease in dogs. I will do anything to stop this from hurting or killing anyone else's baby. for flea and ticks? Simparica trio is a de-worming medication. Started in February and within a couple of weeks ears started twitching. In clinical trials, vomiting and diarrhea were the most frequently reported adverse reactions. How long did the itchiness last for your schnauzer? In the meantime i keep trying to give him ice and i am very worried that i have permanently harmed him. Omg my girl goes threw incredible itching this has lead to us takeing her to the vet because she gets infected from scratching herself to death. In isolated cases, however, dogs displayed more serious reactions such as tremors, muscle twitching, and seizures. Sometimes I think he is either blind or deaf. So bad that the FDA made them put a huge warning now on the package. He has no appetite. They have become so bad that she cries and whimpers any time she is laying down. My 9 month old puppy started acting very lethargic after taking simparica trio. Duke is 7 month boxer And we have the simpatica on Monday and cant believe this stools Hopefully it doesnt last long. They have increased and worsened over the last 3 months. Would you mind sharing what happened with your pup? This crap is poison! 1 is pregnant I told the vet what can I give the pregnant yorkie she said sampirica sold me a 3 month supple for her. I recently switched my 3.5 year old German Shepard to simparica and about 2 weeks after his first dose he had two seizures in one night and has NEVER had them before. And im so mad that my vet didn't inform me of the side effects and im so mad I didn't research it myself. How is your puppy doing? Both of them aren't eating like they were. I am SOOO angry! He's experiencing auto-inmune disease symptoms and we were told he is in critical condition. Hi i have only had my pup for about a week and a half i took him to vet and asked what would be safe to use since my pup is only about 11weeks old and weighs 4pds (prob less today) i gave him this medicine last nite and wish i would have seen this post sooner Now i pray he makes it thru the night. Then suddenly dog has diarrhea and it lasted for several days. We talked with Zoetis (the manufacturer of Simparica) after the FDA's announcement to get some concrete numbers on the frequency of these adverse reactions. We rushed him to the emergency vet and they put him on keppra to stop the seizures. https://photos.app.goo.gl/GbP8UmDNBAxJ1m4g8 I feel like we are just waiting for him to pass now. The innovative formula disrupts gamma-aminobutyric acid (GABA) and glutamate receptors, which both play a role in nerve transmissions. The company's thinking must be the profits outweigh the loses from any lawsuits lost its important to note that the law treats animals as property and the fix value of a dog is quite small and limited. Simparica Trio should be given orally once a month at the recommended minimum doses: 0.54 milligrams of sarolaner, 0.011 mlilligrams of moxidectin, and 2.27 milligrams of pyrantel per pound of body weight. Random vomitting is no fun either. 38 results for "simparica trio for dogs" RESULTS. 4.3 4.3 out of 5 stars (34,534) $39.98 $ 39. Now Im scared ive been giving him Simparica Trio and it could be the cause of his progressively worsening sickness. Doctor prescribed the salyien with some injunction but all are in vain..my labrador has same issues till datemy vet.not says anything about the side effect of the Simparica..i m now helpless..pls help me what should I do.. please help me to rid over itpls pls ..guide me. This was January 15 of 2020. DO NOT give this poison to your pets. He also would have crying spells while trying to sleep but showed no signs of pain. Our 3 mo.old Boston Terrier, 10 lbs, had her first dose of Simparaco yesterday. No this puppy hasnt had seizures and I came to this forum to see other problems with this medicine. My vet seems skeptical that this is related to simparica but it seems clear to me, although I realize that anecdotal cases don't prove it. 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