Eden - Spawns 3 items from any pools, you can only take 1, The Lost - Useless items like HP upgrades, spectral tears or flight are removed from the item pools, Lilith - Causes all your offensive familiars to stack tightly infront of Lilith for more controlled damage, Apollyon - Void has a chance to spawn a previously destroyed item as well. Item Pool At 1 charge it deals 48 damage to any enemies close to Isaac. . This means if you roll into The Lost, changing back to another character will leave you with only 1/2 of a soul heart, Cannot turn you into a character that isn't unlocked yet, Also includes Lazarus II (Lazarus' revived form) and Dark Judas (effect of Judas' Shadow), It's also possible that this item will pick the same character, making it seem like nothing happened, *, grey, gray, black, remote, zapper, changer, building, A one time use item that when used will explode all objects (i.e. (page 5, column 6, row 3)(page 5, column 7, row 3) +2 flat damage to tears fired from Isaac's left eye. Any subsequent hits give +0.4 Tears Up and will ignore the normal fire rate cap, Greatly decreases damage (x0.33 damage multiplier), Individual tears gain random worm effects (e.g. Brimstone they called it raining down: the cities of the plain: Sodom, Gomorrah, Edom. If picked up by Cain, it shoots blood tears and the damage becomes increased to 5 (instead of the usual 3.5), UNLOCK: Unlock this item by beating the Dark Room with Cain, * golden chest pool, gold chest pool, item room, treasure room, item room pool, follower, everyone knows it's abel, brown, grey, gray, dead, head, grey, green cain and abel cain & abel, UNLOCK: Unlock this item by beating Challenge #14 (It's in the Cards), * item room, treasure room, item room pool, bloody, silver, grey, gray, sharp, Item Pool: Item Room, Secret Room, Bomb Beggar, * secret room pool, item room, treasure room, item room pool, smile, face, grinning, doitfgt, REPENTANCE - The list of possible tear effects was updated in Repentance, to include all missing and new ones, * item room, treasure room, item room pool, pink note, money, cash, three dollar bill, Acts like a Shooter, except they shoot out a Brimstone shot. They also retain most of your bomb synergizing items, This item causes your bombs to stick to enemies and when exploding will leave white creep on the ground which slows enemies, When one of your bombs kills an enemy, a bunch of blue spiders are spawned to fight by your side, which deal x2 your current damage, Item Pool: Item Room, Greed Mode Item Room, Bomb Beggar, Bomb Beggar, Shooting in one direction increases your fire rate until a cap is reached, The maximum effect is to halve your delay, which takes roughly 10 seconds to achieve, The accuracy of your tears is also reduced as your fire rate increases, As soon as you change firing direction, your fire rate is reset to its normal amount, Tears will now travel through walls and appear out of the opposite wall, similar to a portal-type mechanic, Your tears can now also travel over rocks and objects in the environment, Spawns 3 random types of hearts on the floor, *, pink, blonde, yellow, red, bow, baby mr dolly, Causes Isaac to spawn 6 troll bombs on the floor every time he gets hit, similar to the Anarchist Cookbook mechanic, Doesn't trigger on damage taken from blood donation machines and devil beggars (but still triggers on other forms of intentional self damage such as IV Bag), Item Pool: Item Room, Red Chest, Curse Room, Greed Mode Item Room, *, blue, orange, poster, torn, paper, page, ripped, A familiar baby that has a random chance to drop a battery pickup or freeze all enemies in the room for a short while, Charged Baby also has a chance to add one charge to your spacebar item, These effects can only occur while in a hostile room with enemies, Gives Isaac a +25% damage up for every tear that successfully hits an enemy, The bonus from Dead Eye maxes out at double your damage (+100%), If a tear misses an enemy, there is a chance for the multiplier to be reset back to 1. 'One Makes you Larger' pills, Magic Mushroom etc, *, mtg, card, magic, gathering, green, brown, giant growth, Spawns 3 random cards on the floor when used, When used, this card will slow down enemies, Isaac's tears by -1 Shot Speed, but speed up Isaac's movement speed by +0.50 for the rest of the current room, UNLOCK: Unlock this item by getting both the Broken Watch and the Stop Watch in your collection, When used, removes the price tag from all items in the current shop or devil deal, making everything free, The effect of the Credit Card only lasts for the current room, UNLOCK: Unlock this card by beating Challenge #10 (Cursed!). This allows you to stay alive as long as you don't get hit during this 10 second period, After this effect occurs, it cannot activate again until Isaac gains a half or full Soul Heart or a Black Heart. cash money, When used, Isaac gains homing shots and +3.0 Range Up for the current room, Counts as 1 of 3 book items needed towards the Bookworm transormation, * library pool, library room, book room pool, item room, treasure room, item room pool, Monsters ?, Satan and The Lamb as Tainted Blue Baby, Drops 2 bombs at once (only 1 bomb is removed from your total), UNLOCK: Unlock this trinket by defeating Mother as Tainted Blue Baby. The damage done by Glass Cannon is calculated as follows: dmg = (dmg * 10) + 10 (i.e. The angel room spawned by The Stairway item also counts, Giving money to a beggar gives a flame orbital, UNLOCK: Unlock this trinket by defeating Mother as Tainted Bethany, Upon entering each new room, this trinket has a chance to copy one of your current familiars, If you have no familiars instead it will spawn either Brother Bobby or Sister Maggy, UNLOCK: Unlock this trinket by defeating Isaac, ?? They can also make you feel weak, numb, dizzy, or confused. REPENTANCE - White poop from Hallowed Ground is now more durable, similar to golden poop. Each tear has a random size multiplier between 0.9x to 1.33x, but there is no effect on damage. The laser deals damage equal to Isaac's damage and deals damage each tick. The attack can be released only when fully charged. with Brimstone you get 4 lasers, Counts as 1 of 3 spider items needed towards the Spider Baby transformation, * item room, treasure room, item room pool, green, black, +2 Damage Up for tears fired from Isaac's left eye, If playing as Cain or you have an item which modifies which eye you fire tears from, each shot has a 50% chance to do +2 Damage, * item room, treasure room, item room pool, poison, green, brown, bottle, jar, danger, Gives Isaac an eye companion that floats around the room and deals 8 damage per tick on contact with enemies, Damage from Isaac's left eye deal roughly +35% damage, * item room, treasure room, item room pool, red, white, When you take damage, this item recharges one room's worth of charge to your spacebar item, For example, with the D6 you would need to take damage 6 times to fully recharge it, * angel room pool, god room pool, angel room item, shop room pool, shop item pool, ), Prevents your stats from being reduced any more for the rest of the run, e.g. Without any other multi-shot effect, the barrage size becomes 16/19/21 respectively. white, brown, underwear, moms bra, mom bra, Causes an explosion near Isaac which takes away half a heart and does 40 damage all enemies in close proximity, REPENTANCE - Kamikaze now has increased blast damage and radius. Everything is sold for its shop price, e.g. Pickups ?, Satan and The Lamb as Tainted Lazarus, All new chests become locked Golden chests, UNLOCK: Unlock this trinket by defeating Isaac, ?? green, red, bloody, A familiar that follows Isaac and leaves blood creep on the floor as it floats, hurting enemies that walk over it for 2 damage per tick, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, bloody, red, blood clot es un aumento de dao parcial debido a que no solo una de dos lagrimas disparadas tengan mas dao este item es de la pool de habitacion del tesoro , bosses o por el item de polyp este item se aprobecha mas con el item de 20.20 ya que en este caso las probabilidades de que mas de una sola lagrima tenga ese aumento de dao Pretty sure it's supposed to be a room . After killing a 15 enemies, Blood Puppy transforms into an aggressive version that will also attack Isaac by charging at him. Placing a bomb this way will not affect your devil/angel room chances, Lil Dumpy follows Isaac and produces a Butter Bean fart when a projectile or enemy is about to hit Isaac, pushing the enemy back and preventing the damage, After it farts, it flies away, stops following Isaac and has to be picked up again before it will follow again, He also has a second larger detection radius that can randomly trigger from enemy projectiles, The effect only works if Lil Dumpy is following and near Isaac, You have a chance alongside each tear to shoot a red flame, which deals damage to enemies that come in contact with it, Damage starts at x4 your current tear damage, and scales down each time an enemy touches the fire, The chance to create a fire scales with your Luck stat, at +11 Luck you have a 50% chance to shoot one, The flames from this item can destroy shopkeepers, which is handy since doing this once per floor increases your devil/angel room chances slightly. This chance doesnt change if you take further damage, You effectively have a 4.4% chance for every minute that passes after taking damage to die, Self-inflicted damage i.e. Achievements The beam is piercing and spectral, dealing damage to all enemies and ignoring all obstacles in its path. If a pushed enemy hits a rock or wall forcefully enough, they take 10 damage, UNLOCK: Unlock this item by destroying 100 poops, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, item room, Blood Clot DMG + range up . From the creative mind of Edmund McMillen came a dungeon crawler inspired by The Legend of Zelda, loaded with . REPENTANCE - Bombs no longer knock each other around when the player has Fast Bombs, allowing for a more controlled line of explosions. Manage all your favorite fandoms in one place! The only way to remove it is via having a second trinket slot (Mom's Purse, Belly Button) or absorbing it (Marbles, Smelter, Gulp! The longer the button is held the faster Gurdy will fling itself across the screen, Deals a fixed amount of damage depending on charge level, at lowest being ~5 and at max being ~20, Lil Gurdy bounces off of enemies and obstacles, A beggar head which floats around the room and picks up any nearby coins. * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, Characters Spikes and Curse Rooms no longer deal damage, Sharp Plug becomes useless with this item, due to how damage is prevented on Isaac's body, REPENTANCE - Isaac's Heart has a charge attack, which pushes enemies away and fires blood tears in all directions. This update brings more than just fixes, the patch also performed some tweaks and changes to the game's health and armor values of some items, so if after a couple of matches you feel like the game is different . Caves 2: 1 Boss Item + 2 Soul Hearts, Depths 1: 4 Soul hearts. Completion Marks This item has two styles, named "Hat" and "No Hat".The "Hat" style retains the default headgear, while the "No Hat" style hides it.. Updated Sep 14, 2022. Isaac's Heart Loki's Horns Bouncy Tears Homing Tears Tammy's Head Tiny Planet Tough Love The Wiz Incubus Epiphora Dead Eye Pupula Duplex Tractor Beam Evil Eye Dead Tooth Eye of Greed Glaucoma Eye of Belial Ghost Pepper Large Zit Rag Mega's Orbitals aren't affected by her shots. Gives Isaac a little portal familiar, that moves across the screen as you're firing, The portal will suck up any consumables and trinkets it travels over, causing it to become larger and deal more contact damage, When the portal sucks up 4 pickups, it turns into a portal that can be used to teleport to unexplored rooms around the floor. : - Binding of Isaac Binding Of Isaac: Rebirth . The priority list of what will drop from champion enemies in order is as follows: Soul Hearts - When you have no red heart containers and less than 2 soul hearts, Red Hearts (Full hearts) - While at 0.5 red hearts, Red Hearts (Full hearts) - When you have at least half a red heart container empty, Trinkets - If you have no trinkets and there are no trinkets on the ground in the room, Soul Hearts - When you have less than 6 total heart containers of any kind, If none of the above conditions are true, champions will resume dropping their regular pickups, UNLOCK: Unlock this item by defeating Greedier mode with Maggy, Allows you to fire tears diagonally by holding down two of the fire buttons at once, If you are using a gamepad, this item allows you to fire in any direction, The first enemy you kill in each new room will now explode and poison all nearby enemies, causing them to take periodic damage until they also die and explode, If you have lots of enemies near each other this can cause a chain reaction, killing lots of enemies in one go, Gives Isaac a finger which floats infront of him and points in the same direction he is facing or firing. When an enemy touches the halo for couple of seconds, a beam of light will come down and deal a burst of damage to it, The triggered beam also fires in all 4 cardinal directions, dealing damage to anything it touches, Every time Isaac takes damage, the halo grows slightly bigger up to a maximum of 10 times. The chemical signals travel through your blood to the spleen, where many platelets are stored. ), Doesn't show the location of Secret or Super Secret rooms, Room icons will not show if a Curse of the Lost is in effect on the current floor, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, pink, red, Item Pool: Boss Room, Challenge Room, Beggar, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, brown, bowl, grey, gray, poop, fly, Item Pool: Boss Room, Beggar, Challenge Room, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, can, tin, brown, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, brown, sack, bag, fly, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, carton, fly, flies, milk, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, green, bone, lump, yellow. with Lilith, After picking up 15 hearts, Isaac gains a permanent angelic familiar and a soul heart drops, Possible familiars include: Holy Water, Guardian Angel, Sworn Protector, The Relic and Seraphim, It is possible to get multiple followers by continuing to pick up hearts, at intervals of 15 hearts each, After all 5 familiars have spawned, it will just drop a soul heart every 15 hearts collected, UNLOCK: Unlock this item by beating Boss Rush with Lilith, Two items now spawn in each of your item rooms, however only one can be taken and the other will disappear, A crown that replaces normal tears with blue diamond tears while you don't have any empty red heart containers or bone hearts, While the effect is active, tears do double damage and have -0.30 Shot Speed, The crown will glow blue while active, if inactive it will appear grey, The effect will also deactivate for the rest of the current room when you take damage, regardless of your health, When a room clear would otherwise yield no rewards, it now spawns 1-3 pennies, REPENTANCE - Deep Pockets no longer adds a pill/card slot, instead increases money cap to 999, UNLOCK: Unlock this item by beating The Chest floor with Keeper, A flying familiar that bounces around the room with a damaging aura, dealing rapid damage to any enemies inside it and boosting Isaac's tear damage, While standing in the black aura, Isaac has a temporary 1.5x damage multiplier (this will stack if you have more than one Succubus), The aura deals 2.5 damage per tick or about 7.5 - 10 damage per second, UNLOCK: Unlock this item by beating The Lamb with Lilith, Gives you a different tear effect with every tear that you fire, Tear effects include: Anti-Gravity, Ball of Bandages (Lvl 4), Bumbo (Lvl 3), Continuum, Cupid's Arrow, Compound Fracture, Euthanasia, Explosivo, Eye of Greed, Fire Mind, Flat Stone, Flat Worm, God's Flesh, Godhead, Head of the Keeper, Holy Light, Hook Worm, Ipecac, Iron Bar, Jacob's Ladder, Knockout Drops, Lachryphagy, Little Horn, Lodestone, Mom's Contacts, Mom's Eyeshadow, Mom's Perfume, Mucormycosis, My Reflection, Mysterious Liquid, Ocular Rift, Ouija Board, Ouroboros Worm, The Parasite, Parasitoid, Polyphemus, Pop!, Proptosis, Pulse Worm, Ring Worm, Rotten Tomato, Rubber Cement, Serpent's Kiss, Sinus Infection, Spider Bite, Strange Attractor, Sulfuric Acid, Technology Zero, Tiny Planet, Trisagion and Wiggle Worm, With Dr. Fetus, this item will also cycle through random Bomb Modifiers (e.g. See the dedicated Devil room page for more details, Reveals the entire map and shows the icons for every room which has one, This is completely useless if you currently have both the Treasure Map and The Compass, Doubles your current red hearts up to full health, * , the lost item pool, playing, card, white, red, When used, turns all pickups, chests and non-boss enemies in the room into Bombs, UNLOCK: Unlock this item by getting a 3 win streak, When used, turns all pickups, chests and non-boss enemies in the room into Coins, UNLOCK: Unlock this item by defeating The Lamb in under 20 minutes, When used, turns all pickups, chests and non-boss enemies in the room into Keys, UNLOCK: Unlock this item by defeating The Lamb without taking hearts, coins and bombs, When used, turns all pickups, chests and non-boss enemies in the room into Hearts, UNLOCK: Unlock this item by defeating any floor after Basement I with only half a heart of health (works as The Lost), Teleports you to the Devil Deal Room on the current floor, When used, instantly kills you and spawns 10 pickup on the floor, Each of the 10 things spawned can be any type of consumable or sometimes a pedestal item (up to a maximum of 3 pedestal items), Any pedestal item created by Suicide King will be related to the room where it was used, meaning that using it in the Angel room will spawn Angel room items, UNLOCK: Unlock this card by beating Challenge #7 (Suicide King), UNLOCK: Unlock this card by defeating Mega Satan as Tainted Magdalene, A card which can be thrown as a projectile directly infront of Isaac, instantly killing anything it hits, including most bosses, If thrown at a multi-phase boss with multiple forms such Satan, Mega Satan or Hush it will only kill that particular phase of the boss, If thrown at a multi-phase boss that works from a single health bar such as Isaac, ??? 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